Mullerian adenosarcomas are rare mixed tumors with low malignant potential,\nand occur mainly in the uterus. Primary adenosarcomas arising in vaginal\nendometriosis are even more rarely reported. We report a very rare case\nwith Müllerian adenosarcoma arising from vaginal endometriosis. A\n43-year-old nulliparous woman has a history of endometriosis. Due to two\nparallel fistulas in cervix, severe endometriosis and adenosarcoma, she has\nundergone radical and multiple surgeries. After the surgery, persistent vaginal\nvault masses were noticed, and eight resections of the polyps at vaginal stump\nwere performed. For the first six resections, all the pathological examinations\nshowed endometriosis. And the last two resections demonstrated vaginal\nadenosarcoma. Transition between Müllerian adenosarcoma and endometriosis\nwas gradual. Finally, adenosarcoma associated with endometriosis was\ndiagnosed from recurrent vaginal masses. To our knowledge, this report is\nthe sixth case that primary adenosarcomas arising in vaginal endometriosis.\nBut chemo-therapy and radiation therapy were not taken and the patient remained\nin a good condition throughout the 9-year follow-up period. In addition,\nwe present a review of the literature. The diagnosis and treatment of the\ntumor are also discussed.
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